Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 11/20 | 0.65 |
| ▸ | MMP12 | P39900 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27945856 | 0.83 | CTSA (0.66) | CTSA | |
| SCHEMBL12804187 | 0.79 | CTSA (1.00) | CTSAMMP12MMP3MMP9MMP8 | |
| SCHEMBL15637633 | 0.74 | CTSA (1.00) | CTSAMMP12MMP3MMP9MMP8 | |
| SCHEMBL12498839 | 0.72 | CTSA (0.85) | CTSA | |
| SCHEMBL12498844 | 0.72 | CTSA (0.85) | CTSA | |
| SCHEMBL12498665 | 0.71 | CTSA (1.00) | CTSA | |
| SCHEMBL27761114 | 0.70 | CTSA (0.62) | CTSAMMP12MMP3MMP9MMP8 | |
| SCHEMBL28114412 | 0.69 | CTSA (0.37) | CTSAEGLN1 | |
| SCHEMBL28100150 | 0.68 | SCNN1A (0.33) | — | |
| SCHEMBL5926688 | 0.67 | CTSA (0.58) | CTSAMMP12MMP3MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103442712-A | Substituted 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals | SANOFI SA | 2013-12-11 | — | — | CN | claimed |
| CN-103442712-A | Substituted 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals | SANOFI SA | 2013-12-11 | — | — | CN | disclosed |