Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 3/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.33 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | CD38 | P28907 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28114873 | 0.85 | SMN1; SMN2 (0.33) | CTSAPPARGPPARAGRM5HSP90AA1 | |
| SCHEMBL28114421 | 0.85 | SMN1; SMN2 (0.33) | CTSAPPARGPPARAGRM5HSP90AA1 | |
| SCHEMBL28114422 | 0.85 | SMN1; SMN2 (0.33) | CTSAPPARGPPARAGRM5HSP90AA1 | |
| SCHEMBL27945856 | 0.77 | CTSA (0.66) | CTSA | |
| SCHEMBL27927676 | 0.69 | CTSA (0.65) | CTSAEGLN1 | |
| SCHEMBL27832481 | 0.68 | MEN1 (0.33) | TP53 | |
| SCHEMBL28100150 | 0.67 | SCNN1A (0.33) | FTOSMN1; SMN2TP53MAPT | |
| SCHEMBL17101388 | 0.65 | CTSA (0.53) | CTSAFTOGRM5SMN1; SMN2MAPT | |
| SCHEMBL27798423 | 0.65 | CYP1A2 (0.36) | FTOPOLBTP53MAPT | |
| SCHEMBL27819607 | 0.64 | NPSR1 (0.41) | FTOSMN1; SMN2TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106103423-A | Chemical compound | 阿斯利康(瑞典)有限公司 | 2016-11-09 | — | — | CN | disclosed |