Maleic Anhydride

Maleic Anhydride

SCHEMBL27927751

C=C(C)C(=O)OCCCC.C=CC(N)=O.O=C1C=CC(=O)O1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.50
HPGD P15428 2/20 0.42
TDP1 Q9NUW8 2/20 0.40
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40
THRB P10828 2/20 0.38
ALDH1A1 P00352 2/20 0.36
ATM Q13315 1/20 0.34
LMNA P02545 2/20 0.34
CYP1A2 P05177 2/20 0.34
CYP2C19 P33261 2/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
PDE4D Q08499 1/20 0.34
XDH P47989 1/20 0.34
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maleic Anhydride SCHEMBL5505199 0.91 TSHR (0.60) TSHRHPGDTDP1POLBAPEX1
Maleic Anhydride SCHEMBL5510071 0.88 TSHR (0.48) TSHRHPGDTDP1POLBAPEX1
Acrylamide SCHEMBL27075744 0.86 TSHR (0.66) TSHRHPGDTDP1POLBAPEX1
Maleic Anhydride SCHEMBL9791857 0.86 TSHR (0.60) TSHRHPGDTDP1POLBAPEX1
Maleic Anhydride SCHEMBL5510723 0.85 TSHR (0.54) TSHRHPGDTDP1POLBAPEX1
Maleic Anhydride SCHEMBL27560872 0.85 TSHR (0.71) TSHRTDP1POLBAPEX1HTT
Maleic Anhydride SCHEMBL26180922 0.85 TSHR (0.71) TSHRTDP1POLBAPEX1HTT
Maleic Anhydride SCHEMBL6702917 0.85 TSHR (0.71) TSHRTDP1POLBAPEX1HTT
Maleic Anhydride SCHEMBL8721383 0.85 TSHR (0.71) TSHRTDP1POLBAPEX1HTT
Styrene SCHEMBL5391027 0.83 TSHR (0.46) TSHRHPGDTDP1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117430971-A Preparation method of heavy calcium carbonate with ultralow oil absorption value 厦门稀土材料研究所 2024-01-23 CN disclosed
CN-103421142-A Ground calcium carbonate powder surface modification method UNIV HEZHOU 2013-12-04 CN disclosed