Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Anhydride SCHEMBL5504158 | 0.90 | TSHR (0.54) | TSHRHPGDTDP1POLBAPEX1 | |
| Maleic Anhydride SCHEMBL5506367 | 0.89 | TSHR (0.61) | TSHRHPGDTDP1THRBATM | |
| Maleic Anhydride SCHEMBL5510723 | 0.89 | TSHR (0.54) | TSHRHPGDTDP1POLBAPEX1 | |
| Maleic Anhydride SCHEMBL5505199 | 0.88 | TSHR (0.60) | TSHRHPGDTDP1POLBAPEX1 | |
| Maleic Anhydride SCHEMBL27927751 | 0.88 | TSHR (0.50) | TSHRHPGDTDP1POLBAPEX1 | |
| Acrylic Acid Methyl Ester SCHEMBL8365310 | 0.87 | TSHR (0.62) | TSHRHPGDTDP1POLBAPEX1 | |
| Maleic Anhydride SCHEMBL5506494 | 0.85 | TSHR (0.40) | TSHRHPGDTDP1POLBAPEX1 | |
| Acrylic Acid Methyl Ester SCHEMBL27763453 | 0.84 | TSHR (0.58) | TSHRHPGDTDP1POLBAPEX1 | |
| Acrylic Acid Methyl Ester SCHEMBL28097602 | 0.84 | TSHR (0.67) | TSHRHPGDTDP1POLBAPEX1 | |
| Maleic Anhydride SCHEMBL9791857 | 0.84 | TSHR (0.60) | TSHRHPGDTDP1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070117936-A1 | Polymeric end-capping reagent for carbon dioxide-epoxide copolymers and a method for preparing the same | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCE | 2007-05-24 | — | — | US | disclosed |