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Sugi Predict / Compounds / SCHEMBL279281

SCHEMBL279281

SCHEMBL279281

COC(=O)OCc1ccc(N(c2ccc(C)c(C)c2)c2ccc(C)c(C)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 5/20 0.43
▸ ALDH1A1 P00352 4/20 0.43
▸ NPC1 O15118 3/20 0.43
▸ KDM4E B2RXH2 3/20 0.43
▸ MAPK1 P28482 2/20 0.43
▸ HPGD P15428 2/20 0.43
▸ TSHR P16473 2/20 0.43
▸ GAA P10253 1/20 0.43
▸ HSD17B10 Q99714 1/20 0.43
▸ MEN1 O00255 2/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ LMNA P02545 2/20 0.39
▸ SIRT5 Q9NXA8 1/20 0.39
▸ RAB9A P51151 3/20 0.39
▸ KCNH2 Q12809 1/20 0.38
▸ MAPT P10636 2/20 0.36
▸ RECQL P46063 1/20 0.36
▸ TAS1R3 Q7RTX0 1/20 0.36
▸ TAS1R1 Q7RTX1 1/20 0.36
▸ HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL279306 0.88 ALDH1A1 (0.51) SMN1; SMN2ALDH1A1NPC1KDM4EMAPK1
SCHEMBL279030 0.88 ALDH1A1 (0.36) SMN1; SMN2ALDH1A1NPC1KDM4EMAPK1
SCHEMBL279505 0.86 SMN1; SMN2 (0.39) SMN1; SMN2ALDH1A1NPC1KDM4EMAPK1
SCHEMBL15080675 0.85 ALDH1A1 (0.49) SMN1; SMN2ALDH1A1NPC1KDM4EMAPK1
SCHEMBL14063391 0.85 ALDH1A1 (0.49) SMN1; SMN2ALDH1A1NPC1KDM4EMAPK1
SCHEMBL279194 0.85 ALDH1A1 (0.47) SMN1; SMN2ALDH1A1NPC1KDM4EMAPK1
SCHEMBL279308 0.82 ALDH1A1 (0.48) SMN1; SMN2ALDH1A1NPC1KDM4EMAPK1
SCHEMBL279338 0.82 ALDH1A1 (0.48) SMN1; SMN2ALDH1A1NPC1KDM4EMAPK1
SCHEMBL14063418 0.82 ALDH1A1 (0.45) SMN1; SMN2ALDH1A1NPC1KDM4EMAPK1
SCHEMBL15080652 0.81 ALDH1A1 (0.43) SMN1; SMN2ALDH1A1NPC1KDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8475982-B2 Charge-transporting compound, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2013-07-02 — — US disclosed
US-8475982-B2 Charge-transporting compound, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2013-07-02 — — US disclosed
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 — — US disclosed
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 — — US disclosed
US-8273517-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-09-25 — — US disclosed
US-8273517-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-09-25 — — US disclosed
US-8263299-B2 Multilayer; electroconductive support, photosensitive layer of cured phenolic resin having dynamics hardness and elastic deformation; xerography;thin film with few defects;mechanical strength; stability; high quality images FUJI XEROX CO., LTD. (JP) 2012-09-11 — — US disclosed
US-8263299-B2 Multilayer; electroconductive support, photosensitive layer of cured phenolic resin having dynamics hardness and elastic deformation; xerography;thin film with few defects;mechanical strength; stability; high quality images FUJI XEROX CO., LTD. (JP) 2012-09-11 — — US disclosed
US-20120134713-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-05-31 — — US disclosed
US-20120134713-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-05-31 — — US disclosed
US-20080261135-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2008-10-23 — — US disclosed
US-20080261135-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2008-10-23 — — US disclosed
US-20080220356-A1 Electrophotographic photoreceptor, process cartridge and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2008-09-11 — — US disclosed
US-20080220356-A1 Electrophotographic photoreceptor, process cartridge and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2008-09-11 — — US disclosed
US-20080031642-A1 Electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2008-02-07 — — US disclosed
US-20080031642-A1 Electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2008-02-07 — — US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 — — US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 — — US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 — — US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 — — US disclosed