SCHEMBL27928635

SCHEMBL27928635

Sc1c(Cl)cccc1Cl.[KH]

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.47
CYP1A2 P05177 3/20 0.47
TSHR P16473 4/20 0.47
LMNA P02545 1/20 0.47
ALDH1A1 P00352 4/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
IDO1 P14902 1/20 0.38
TAAR1 Q96RJ0 1/20 0.36
PNMT P11086 1/20 0.36
NR4A2 P43354 1/20 0.36
AKR1B1 P15121 1/20 0.33
AHR P35869 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL190658 0.97
SCHEMBL1968215 0.81
SCHEMBL8487863 0.77 CYP1A2 (0.35) CYP2A6CYP1A2TSHRLMNAALDH1A1
SCHEMBL3658340 0.77
SCHEMBL15352112 0.77
SCHEMBL283996 0.77
SCHEMBL14652683 0.77
SCHEMBL28239976 0.77
SCHEMBL28809666 0.75 ALDH1A1 (0.39) CYP2A6CYP1A2TSHRLMNAALDH1A1
Hydrochloric Acid SCHEMBL2001788 0.75 TSHR (0.52) CYP2A6CYP1A2TSHRLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103180045-B Novel olefin metathesis catalysts BERGEN TEKNOLOGIOVERFORING A/S (NO) 2016-04-13 CN disclosed
CN-103180045-A Novel olefin metathesis catalysts BERGEN TEKNOLOGIOVERFOERING AS 2013-06-26 CN disclosed