Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
| ▸ | METAP2 | P50579 | 1/20 | 0.57 |
| ▸ | METAP1 | P53582 | 1/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.56 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7689718 | 0.87 | PARP1 (0.56) | KDM4EKMT2AATMHSP90AA1MAPT | |
| SCHEMBL28507152 | 0.85 | KDM4E (0.59) | KDM4EKMT2AHSP90AA1MAPTLMNA | |
| SCHEMBL15053947 | 0.81 | KDM4E (0.61) | KDM4EKMT2AHSP90AA1MAPTBRD4 | |
| SCHEMBL29448814 | 0.80 | KDM4E (0.59) | KDM4EHSP90AA1PARP1RPS6KB1HTT | |
| SCHEMBL27767795 | 0.80 | KDM4E (0.64) | KDM4EPARP1RPS6KB1L3MBTL1 | |
| SCHEMBL20515237 | 0.80 | KDM4E (0.59) | KDM4EKMT2AHSP90AA1MAPTPARP1 | |
| SCHEMBL18979963 | 0.79 | PARP1 (0.49) | KDM4EKMT2AATMPARP1RPS6KB1 | |
| SCHEMBL27947200 | 0.76 | RPS6KB1 (0.58) | KDM4EPARP1RPS6KB1L3MBTL1 | |
| SCHEMBL196536 | 0.76 | KDM4E (0.70) | KDM4EKMT2AHSP90AA1MAPTLMNA | |
| SCHEMBL6218744 | 0.75 | KDM4E (0.52) | KDM4EKMT2AHSP90AA1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103492028-A | Novel sulfonaminoquinoline hepcidin antagonists | VIFOR INT AG | 2014-01-01 | — | — | CN | disclosed |