Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | RPS6KB1 | P23443 | 9/20 | 0.49 |
| ▸ | AURKA | O14965 | 6/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CD38 | P28907 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27930130 | 0.87 | KDM4E (0.59) | PARP1KDM4EL3MBTL1KMT2AATM | |
| SCHEMBL5762503 | 0.85 | KDM4E (0.54) | KDM4EL3MBTL1KMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7692358 | 0.83 | KDM4E (0.50) | KDM4EL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL10126261 | 0.81 | PARP1 (0.57) | PARP1KDM4EL3MBTL1RPS6KB1AURKA | |
| SCHEMBL30380500 | 0.81 | KDM4E (0.66) | PARP1KDM4EL3MBTL1ALDH1A1RPS6KB1 | |
| SCHEMBL27559735 | 0.81 | KDM4E (0.48) | KDM4EL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL4511366 | 0.80 | L3MBTL1 (0.69) | PARP1KDM4EL3MBTL1KMT2AATM | |
| SCHEMBL23293688 | 0.80 | PSMD14 (0.56) | KDM4EKMT2AATMMEN1ALDH1A1 | |
| SCHEMBL7692480 | 0.80 | KDM4E (0.50) | KDM4EL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL7689021 | 0.77 | KDM4E (0.48) | KDM4EL3MBTL1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000622-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |