Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 15/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | NEK2 | P51955 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3087791 | 0.77 | MET (0.69) | METMEN1KMT2ACHEK1NEK2 | |
| SCHEMBL13561689 | 0.75 | MET (0.74) | METMEN1KMT2ACHEK1NEK2 | |
| SCHEMBL13089798 | 0.74 | MET (0.63) | METMEN1KMT2ACHEK1NEK2 | |
| SCHEMBL1303077 | 0.73 | MET (0.65) | METMEN1KMT2ACHEK1NEK2 | |
| SCHEMBL2466743 | 0.73 | MET (0.65) | METMEN1KMT2ACHEK1NEK2 | |
| SCHEMBL1952616 | 0.71 | MET (0.65) | METMEN1KMT2ACHEK1NEK2 | |
| SCHEMBL13089765 | 0.71 | MEN1 (0.70) | METMEN1KMT2ACHEK1NEK2 | |
| SCHEMBL2465601 | 0.71 | MET (0.62) | MET | |
| SCHEMBL3084164 | 0.70 | MET (1.00) | METMEN1KMT2ACHEK1NEK2 | |
| SCHEMBL4130448 | 0.70 | MET (0.69) | METMEN1KMT2ACHEK1NEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101743241-B | Pyridazinone derivates | MERCK PATENT GMBH | 2013-12-25 | — | — | CN | disclosed |