Mannitol

Mannitol

SCHEMBL27930692

O=C(O)c1cccnc1.OCC(O)C(O)C(O)C(O)CO

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.68
APP P05067 1/20 0.68
GAA P10253 1/20 0.68
HCAR3 P49019 1/20 0.68
HCAR2 Q8TDS4 1/20 0.68
PLOD2 O00469 2/20 0.50
THRB P10828 1/20 0.49
KMO O15229 1/20 0.47
F7 P08709 1/20 0.47
F3 P13726 1/20 0.47
SARM1 Q6SZW1 1/20 0.47
SIRT2 Q8IXJ6 1/20 0.47
SIRT6 Q8N6T7 1/20 0.47
SIRT1 Q96EB6 1/20 0.47
SIRT3 Q9NTG7 1/20 0.47
SIRT5 Q9NXA8 1/20 0.47
SIRT4 Q9Y6E7 1/20 0.47
KDM4E B2RXH2 1/20 0.46
MKNK1 Q9BUB5 1/20 0.46
MKNK2 Q9HBH9 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sorbitol SCHEMBL31414236 1.00 ALDH1A1 (0.68) ALDH1A1APPGAAHCAR3HCAR2
Demannose SCHEMBL27396064 0.90 ALDH1A1 (0.55) ALDH1A1APPGAAHCAR3HCAR2
Xylose SCHEMBL27986605 0.89 ALDH1A1 (0.57) ALDH1A1APPGAAHCAR3HCAR2
Niacin SCHEMBL11225937 0.88 ALDH1A1 (0.53) ALDH1A1APPGAAHCAR3HCAR2
Niacin SCHEMBL28582355 0.87 ALDH1A1 (0.72) ALDH1A1APPGAAHCAR3HCAR2
Mannitol SCHEMBL9807801 0.86 F7 (0.69) ALDH1A1APPGAAHCAR3HCAR2
Niacin SCHEMBL29047533 0.85 ALDH1A1 (0.70) ALDH1A1APPGAAHCAR3HCAR2
Mannitol SCHEMBL21807508 0.84 F7 (0.61) ALDH1A1APPGAAHCAR3HCAR2
Niacin SCHEMBL810524 0.83 ALDH1A1 (0.57) ALDH1A1APPGAAHCAR3HCAR2
Niacin SCHEMBL29047499 0.83 ALDH1A1 (0.84) ALDH1A1APPGAAHCAR3HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119792545-A Pharmaceutical carrier, micelle, anti-inflammatory and/or anti-atherosclerosis pharmaceutical preparation, and preparation method and application thereof 上海市第一人民医院 2025-04-11 CN claimed
CN-119792539-A Medicine carrier based on gallic acid-vitamin E polyethylene glycol succinate, micelle, preparation method and application thereof 上海市第一人民医院 2025-04-11 CN claimed
CN-119823034-A Preparation method of manna hexanicotinate 华中药业股份有限公司 2025-04-15 CN disclosed
CN-119792545-A Pharmaceutical carrier, micelle, anti-inflammatory and/or anti-atherosclerosis pharmaceutical preparation, and preparation method and application thereof 上海市第一人民医院 2025-04-11 CN disclosed
CN-119792539-A Medicine carrier based on gallic acid-vitamin E polyethylene glycol succinate, micelle, preparation method and application thereof 上海市第一人民医院 2025-04-11 CN disclosed
CN-119569649-A Preparation method of high-purity mannopyranate 华中药业股份有限公司 2025-03-07 CN disclosed
CN-113527527-A Method for extracting algal polysaccharide through continuous phase change 深圳职业技术学院 2021-10-22 CN disclosed
CN-113493409-A Process method for preparing polyol nicotinate compound 上海应用技术大学 2021-10-12 CN disclosed
CN-103819399-B A kind of method of producing high purity sweet dew six cigarette ester QINGDAO SHOUHE JINHAI PHARMACEUTICAL CO., LTD. (CN) 2015-10-14 CN disclosed
CN-103570611-B Novel compound, and preparation method and application thereof QINGDAO SHOUHE JINHAO PHARMACEUTICAL CO LTD 2014-08-27 CN disclosed
CN-103570611-B Novel compound, and preparation method and application thereof QINGDAO SHOUHE JINHAO PHARMACEUTICAL CO LTD 2014-08-27 CN disclosed
CN-103499648-B Mannitol nicotinate quality control method QINGDAO SHOUHEJINHAI PHARMACEUTICAL CO LTD 2014-06-11 CN disclosed
CN-103499648-B Mannitol nicotinate quality control method QINGDAO SHOUHEJINHAI PHARMACEUTICAL CO LTD 2014-06-11 CN disclosed
CN-103499648-B Mannitol nicotinate quality control method QINGDAO SHOUHEJINHAI PHARMACEUTICAL CO LTD 2014-06-11 CN disclosed
CN-103819399-A Method for producing high-purity mannityl nicotinate QINGDAO SHOUHE JINHAI PHARMACEUTICAL CO LTD 2014-05-28 CN disclosed
CN-103570611-A Novel compound, and preparation method and application thereof QINGDAO SHOUHE JINHAO PHARMACEUTICAL CO LTD 2014-02-12 CN disclosed
CN-103570611-A Novel compound, and preparation method and application thereof QINGDAO SHOUHE JINHAO PHARMACEUTICAL CO LTD 2014-02-12 CN disclosed
CN-103499648-A Mannitol nicotinate quality control method QINGDAO SHOUHEJINHAI PHARMACEUTICAL CO LTD 2014-01-08 CN disclosed
CN-103499648-A Mannitol nicotinate quality control method QINGDAO SHOUHEJINHAI PHARMACEUTICAL CO LTD 2014-01-08 CN disclosed
CN-103499648-A Mannitol nicotinate quality control method QINGDAO SHOUHEJINHAI PHARMACEUTICAL CO LTD 2014-01-08 CN disclosed