Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27873206 | 0.83 | KDM4E (0.38) | MAPTNPSR1NPC1RAB9AALDH1A1 | |
| SCHEMBL28069487 | 0.82 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3ADRB1HTR3E | |
| SCHEMBL27555907 | 0.78 | TRIM24 (0.36) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL18892741 | 0.72 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3ADRB1HTR3E | |
| SCHEMBL27760163 | 0.72 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3ADRB1HTR3E | |
| SCHEMBL27528660 | 0.71 | CYP2C19 (0.54) | SIGMAR1MAPTMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL27859961 | 0.71 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3ADRB1HTR3E | |
| SCHEMBL811572 | 0.70 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3ADRB1HTR3E | |
| Hydrochloric Acid SCHEMBL11019504 | 0.70 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3ADRB1HTR3E | |
| SCHEMBL17103110 | 0.69 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3ADRB1HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108276388-A | 1H- indole derivatives and application thereof | 成都医学院 | 2018-07-13 | — | — | CN | disclosed |
| CN-101796055-B | Inhibitors of VEGF receptor and HGF receptor signaling | METHYLGENE INC | 2013-09-04 | — | — | CN | disclosed |