SCHEMBL27760163

SCHEMBL27760163

NC1NCCN1c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.44
SLC6A4 P31645 2/20 0.44
SLC6A3 Q01959 2/20 0.44
ADRB1 P08588 2/20 0.41
SIGMAR1 Q99720 2/20 0.41
HTR3E A5X5Y0 1/20 0.41
HTR3B O95264 1/20 0.41
HTR3A P46098 1/20 0.41
HTR3D Q70Z44 1/20 0.41
HTR3C Q8WXA8 1/20 0.41
MAPT P10636 3/20 0.38
NPSR1 Q6W5P4 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPK1 P28482 2/20 0.36
HTT P42858 1/20 0.35
USP2 O75604 1/20 0.34
CYP2D6 P10635 1/20 0.34
ALOX5 P09917 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11019504 0.98 SLC6A2 (0.42) SLC6A2SLC6A4SLC6A3ADRB1SIGMAR1
SCHEMBL811572 0.74 SLC6A2 (0.42) SLC6A2SLC6A4SLC6A3ADRB1SIGMAR1
Hydrochloric Acid SCHEMBL28523425 0.73 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3ADRB1SIGMAR1
SCHEMBL644788 0.73 SLC6A2 (0.57) SLC6A2SLC6A4SLC6A3ADRB1SIGMAR1
SCHEMBL17103110 0.73 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3ADRB1SIGMAR1
SCHEMBL11369029 0.72 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3ADRB1SIGMAR1
Hydrochloric Acid SCHEMBL28933673 0.72 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3ADRB1SIGMAR1
SCHEMBL2573871 0.72 SLC6A2 (0.44) SLC6A2SLC6A4SLC6A3ADRB1SIGMAR1
SCHEMBL27934278 0.72 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3ADRB1SIGMAR1
SCHEMBL28069487 0.72 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3ADRB1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101500990-A Process for preparing amidrazones BASF AG (DE) 2009-08-05 CN disclosed