Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25420116 | 0.81 | CNR2 (0.59) | CNR2CYP2D6CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL5099923 | 0.77 | GAA (0.50) | PDE4BHDAC6HDAC4TRPV1CSNK2A2 | |
| SCHEMBL6451201 | 0.72 | CNR2 (0.53) | HDAC6HDAC4CNR2CYP2D6CYP2C19 | |
| SCHEMBL16879004 | 0.71 | PIM1 (0.45) | PDE4BIRAK4CSNK2A2CSNK2A1PIM1 | |
| SCHEMBL13503354 | 0.70 | CNR2 (0.62) | CNR2CYP2D6CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL20337733 | 0.70 | WDR5 (0.44) | IRAK4WDR5 | |
| SCHEMBL13503355 | 0.70 | CNR2 (0.61) | CNR2CYP2D6CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL13503356 | 0.70 | CNR2 (0.76) | CNR2CYP2D6CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL13503327 | 0.70 | CNR2 (0.76) | CNR2CYP2D6CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL13503361 | 0.70 | CNR2 (0.76) | CNR2CYP2D6CYP2C19CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103265517-A | 3-substituted coumarin derivative and use thereof | UNIV ZHEJIANG | 2013-08-28 | — | — | CN | disclosed |