Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 7/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3303804 | 0.72 | TP53 (0.54) | MAPTMEN1KMT2ATP53POLB | |
| SCHEMBL3309193 | 0.69 | MAPT (0.63) | MAPTMEN1KMT2ATP53POLB | |
| SCHEMBL3311352 | 0.67 | MAPT (0.60) | MAPTMEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL3316373 | 0.67 | TP53 (0.53) | MAPTMEN1KMT2ATP53POLB | |
| SCHEMBL3309188 | 0.65 | S1PR2 (0.66) | TP53 | |
| SCHEMBL24031014 | 0.65 | PGR (0.65) | — | |
| SCHEMBL24030796 | 0.64 | HDAC1 (0.77) | — | |
| SCHEMBL3307423 | 0.64 | S1PR2 (0.57) | MAPTMEN1KMT2ATP53POLB | |
| SCHEMBL13332657 | 0.63 | TP53 (0.53) | MAPTMEN1KMT2ATP53POLB | |
| SCHEMBL13241824 | 0.63 | POLB (0.62) | MAPTTP53POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101622234-B | Bicyclic organic compounds suitable for the treatment of inflammatory or allergic conditions | NOVARTIS AG | 2013-08-07 | — | — | CN | claimed |