Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | KIF11 | P52732 | 5/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2795435 | 0.94 | CYP2C9 (0.55) | CYP2C9KMT2AMEN1ALDH1A1CES2 | |
| Bromomethane SCHEMBL3169542 | 0.91 | CYP2C9 (0.52) | CYP2C9KMT2AMEN1ALDH1A1CES2 | |
| SCHEMBL28711201 | 0.89 | KMT2A (0.60) | KMT2AMEN1ALDH1A1CES2CES1 | |
| Benzylic Acid SCHEMBL11870645 | 0.86 | CYP2C9 (0.63) | CYP2C9KMT2AMEN1ALDH1A1CES1 | |
| SCHEMBL2319756 | 0.86 | KMT2A (0.54) | KMT2AMEN1ALDH1A1CES2CES1 | |
| SCHEMBL14166571 | 0.84 | CYP2C9 (0.49) | CYP2C9KMT2AMEN1ALDH1A1CES2 | |
| SCHEMBL6203510 | 0.84 | CES1 (0.56) | KMT2AMEN1ALDH1A1CES2CES1 | |
| SCHEMBL6045338 | 0.83 | KCNN4 (0.55) | KMT2AMEN1ALDH1A1CES2CES1 | |
| SCHEMBL23828851 | 0.83 | KMT2A (0.51) | KMT2AMEN1ALDH1A1CES2CES1 | |
| Benzylic Acid SCHEMBL7066 | 0.82 | CYP2C9 (0.74) | CYP2C9KMT2AALDH1A1CYP2D6HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108901-A | Synthetic method of alpha-hydroxycarboxylic acid compound | 四川大学 | 2022-09-27 | — | — | CN | disclosed |
| US-8084463-B2 | Quinuclidine derivatives and their use as muscarinic M3 receptor antagonists | NOVARTIS AG (CH) | 2011-12-27 | — | — | US | disclosed |
| US-20100249451-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED BENZILIC ACID FROM SUBSTITUTED BENZILS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-09-30 | — | — | US | disclosed |
| EP-1811999-B1 | QUINUCLIDINE DERIVATIVES AND THEIR USE AS MUSCARINIC M3 RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2010-09-15 | — | — | EP | disclosed |
| EP-2206499-A1 | QUINUCLIDINE DERIVATIVES AND THEIR USE AS MUSCARINIC M3 RECEPTOR ANTAGONISTS | Novartis AG (CH) | 2010-07-14 | — | — | EP | disclosed |
| US-20100168132-A1 | QUINUCLIDINE DERIVATIVES AND THEIR USE AS MUSCARINIC M3 RECEPTOR ANTAGONISTS | PRESS NEIL JOHN | 2010-07-01 | — | — | US | disclosed |
| US-7723356-B2 | Quinuclidine derivatives and their use as muscarinic m3 receptor antagonists | NOVARTIS AG (CH) | 2010-05-25 | — | — | US | disclosed |
| US-20090048281-A1 | (R)-3-(2-Cyclohexyl-2-hydroxy-2-phenyl-acetoxy)-1-(isoxazol-3-ylcarbamoylmethyl)-1-azonia-bicyclo[2.2.2] octane, useful for treating inflammatory or obstructive airways diseases | NOVARTIS AG (CH) | 2009-02-19 | — | — | US | disclosed |
| EP-1811999-A1 | QUINUCLIDINE DERIVATIVES AND THEIR USE AS MUSCARINIC M3 RECEPTOR ANTAGONISTS | Novartis AG (CH) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006048225-A1 | QUINUCLIDINE DERIVATIVES AND THEIR USE AS MUSCARINIC M3 RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2006-05-11 | — | — | WO | disclosed |
| US-4126468-A | Radiation sensitive compositions of quaternary ammonium salt and carboxylic acid sensitizer | VICKERS LIMITED (GB) | 1978-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249451-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED BENZILIC ACID FROM SUBSTITUTED BENZILS | KCNC1, HRH2, SMARCC2 | CYP2C9 400/4885KMT2A 320/4885MEN1 3333/4885 |
| US-20090048281-A1 | (R)-3-(2-Cyclohexyl-2-hydroxy-2-phenyl-acetoxy)-1-(isoxazol-3-ylcarbamoylmethyl)-1-azonia-bicyclo[2.2.2] octane, useful for treating inflammatory or obstructive airways diseases | CHRM3, CHRM2, CHRM1 | CYP2C9 1533/4885KMT2A 2413/4885MEN1 4480/4885 |
| US-20100168132-A1 | QUINUCLIDINE DERIVATIVES AND THEIR USE AS MUSCARINIC M3 RECEPTOR ANTAGONISTS | CHRM3, CHRM2, CHRM1 | CYP2C9 1459/4885KMT2A 1968/4885MEN1 2183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.