Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | ACP1 | P24666 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10270066 | 0.85 | KDM4E (0.60) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL10612809 | 0.78 | KDM4E (0.59) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL29726798 | 0.78 | MEN1 (0.57) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL3866490 | 0.78 | MEN1 (0.59) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL13048536 | 0.78 | MEN1 (0.57) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL16305319 | 0.78 | MEN1 (0.57) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL29445834 | 0.78 | MEN1 (0.59) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL27914382 | 0.77 | ACHE (0.58) | KDM4EHPGDSMN1; SMN2LMNA | |
| SCHEMBL23052940 | 0.75 | MEN1 (0.59) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL4461418 | 0.75 | KDM4E (0.74) | KDM4EALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103254244-A | Aryl five-membered heterocyclic substituted quinoline platinum (II) complex, preparation method thereof and application | UNIV TAIYUAN TECHNOLOGY | 2013-08-21 | — | — | CN | disclosed |
| CN-103242369-A | Aromatic five-membered heterocyclo-substituted quinoline iridium (III) complex as well as preparation method and application thereof | UNIV TAIYUAN TECHNOLOGY | 2013-08-14 | — | — | CN | disclosed |