Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10012640 | 0.94 | DRD2 (0.51) | DRD2SIGMAR1DRD3 | |
| SCHEMBL1654652 | 0.93 | DRD2 (0.52) | DRD2SIGMAR1DRD3 | |
| SCHEMBL10012965 | 0.84 | DRD2 (0.43) | DRD2SIGMAR1DRD3 | |
| SCHEMBL10011586 | 0.81 | DRD2 (0.41) | DRD2DRD3 | |
| SCHEMBL27935081 | 0.81 | CYP3A4 (0.46) | — | |
| SCHEMBL12781936 | 0.80 | DRD2 (0.41) | DRD2SIGMAR1DRD3 | |
| SCHEMBL27949680 | 0.77 | CYP3A4 (0.41) | — | |
| SCHEMBL1654200 | 0.75 | CYP3A4 (0.47) | — | |
| SCHEMBL10013000 | 0.74 | CYP3A4 (0.46) | — | |
| SCHEMBL17861451 | 0.73 | DRD2 (0.60) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103459390-A | Macrocyclic integrase inhibitors for use in the treatment of feline immunodeficiency virus | ELANCO ANIMAL HEALTH IRELAND | 2013-12-18 | — | — | CN | disclosed |