SCHEMBL27934859

SCHEMBL27934859

CC(Cl)c1cccc2cc3ccccc3cc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.39
KDM4E B2RXH2 2/20 0.39
GAA P10253 2/20 0.39
HSD17B10 Q99714 2/20 0.37
HIF1A Q16665 1/20 0.37
CYP1B1 Q16678 1/20 0.37
CYP1A2 P05177 4/20 0.36
CYP2C9 P11712 2/20 0.36
NQO1 P15559 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CYP2C19 P33261 1/20 0.36
HPGD P15428 1/20 0.36
MAPT P10636 3/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
HTR2B P41595 1/20 0.35
UGT2B7 P16662 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11739257 0.83 CYP1A2 (0.43) ALDH1A1KDM4EGAAHSD17B10HIF1A
SCHEMBL9858819 0.83 ALDH1A1 (0.41) ALDH1A1KDM4EGAAHSD17B10HIF1A
SCHEMBL5273225 0.83 ALDH1A1 (0.41) ALDH1A1KDM4EGAAHSD17B10HIF1A
SCHEMBL2333290 0.81 ALDH1A1 (0.56) ALDH1A1CYP1A2CYP2C9CYP2C19ADRA2A
SCHEMBL29774251 0.81 ALDH1A1 (0.56) ALDH1A1CYP1A2CYP2C9CYP2C19ADRA2A
SCHEMBL15847899 0.81 ALDH1A1 (0.37) ALDH1A1KDM4EGAAHSD17B10HIF1A
SCHEMBL6677010 0.80 ALDH1A1 (0.43) ALDH1A1KDM4EGAAHSD17B10HIF1A
SCHEMBL1988094 0.80 UGT2B7 (0.47) ALDH1A1KDM4EGAAHSD17B10HIF1A
SCHEMBL22288169 0.80 ALDH1A1 (0.40) ALDH1A1KDM4EGAAHSD17B10HIF1A
SCHEMBL1306163 0.80 ALDH1A1 (0.43) ALDH1A1KDM4EGAAHSD17B10HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103539822-A A synthesis method of cupped metal ring tomato [Rh {9, 10-bis (2-(diphenylphosphino) ethyl) anthracene}-(CO) Cl]3and its application UNIV NANKAI 2014-01-29 CN claimed
CN-103539822-B Synthesis method and application of cup-shaped metal cyclophane [Rh{9,10-di(2-(diphenylphosphino)ethyl)anthracene}-(CO)C1]3 南开大学 2017-05-03 CN disclosed
CN-103539822-A A synthesis method of cupped metal ring tomato [Rh {9, 10-bis (2-(diphenylphosphino) ethyl) anthracene}-(CO) Cl]3and its application UNIV NANKAI 2014-01-29 CN disclosed