Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 5/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.51 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.49 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.49 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27482923 | 0.90 | CCR1 (0.44) | CHRM1CHRM3CHRM2SSTR4MEN1 | |
| SCHEMBL27787058 | 0.81 | CHRM2 (0.54) | CHRM1CHRM3CHRM2SSTR1SSTR4 | |
| SCHEMBL17294645 | 0.80 | CHRM2 (0.56) | CHRM1CHRM3CHRM2SSTR1SSTR4 | |
| SCHEMBL17294627 | 0.80 | CHRM2 (0.58) | CHRM1CHRM3CHRM2SSTR1SSTR4 | |
| SCHEMBL12334720 | 0.77 | EPHX1 (0.53) | CHRM1CHRM3CHRM2SSTR1SSTR4 | |
| SCHEMBL25464159 | 0.75 | HDAC1 (0.49) | CHRM1CHRM3CHRM2SSTR4MEN1 | |
| SCHEMBL6589522 | 0.74 | CHRM2 (0.69) | CHRM1CHRM3CHRM2 | |
| SCHEMBL13592145 | 0.74 | CHRM2 (0.69) | CHRM1CHRM3CHRM2 | |
| Hydrochloric Acid SCHEMBL6588535 | 0.73 | CHRM2 (0.67) | CHRM1CHRM3CHRM2 | |
| SCHEMBL13592129 | 0.73 | CHRM2 (0.67) | CHRM1CHRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103275036-A | Piperidine derivatives and preparation method thereof | ZHU XUEQI | 2013-09-04 | — | — | CN | disclosed |