Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 16/20 | 0.69 |
| ▸ | CHRM1 | P11229 | 16/20 | 0.69 |
| ▸ | CHRM3 | P20309 | 16/20 | 0.69 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13592145 | 1.00 | CHRM2 (0.69) | CHRM2CHRM1CHRM3KEAP1NFE2L2 | |
| SCHEMBL13592129 | 0.99 | CHRM2 (0.67) | CHRM2CHRM1CHRM3KEAP1NFE2L2 | |
| Hydrochloric Acid SCHEMBL6588535 | 0.96 | CHRM2 (0.67) | CHRM2CHRM1CHRM3KEAP1NFE2L2 | |
| SCHEMBL5119960 | 0.92 | CHRM2 (0.60) | CHRM2CHRM1CHRM3KEAP1NFE2L2 | |
| SCHEMBL7471610 | 0.82 | CHRM2 (1.00) | CHRM2CHRM1CHRM3 | |
| SCHEMBL17294627 | 0.81 | CHRM2 (0.58) | CHRM2CHRM1CHRM3 | |
| SCHEMBL5948024 | 0.81 | KEAP1 (0.57) | CHRM2CHRM1CHRM3KEAP1NFE2L2 | |
| SCHEMBL4076565 | 0.81 | KEAP1 (0.57) | CHRM2CHRM1CHRM3KEAP1NFE2L2 | |
| SCHEMBL5948427 | 0.80 | KEAP1 (0.56) | CHRM2CHRM1CHRM3KEAP1NFE2L2 | |
| SCHEMBL5948317 | 0.80 | KEAP1 (0.56) | CHRM2CHRM1CHRM3KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823423-B1 | 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-06-16 | — | — | EP | disclosed |
| EP-0930298-B1 | FLUORINATED 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2002-12-18 | — | — | EP | disclosed |
| EP-0863141-B1 | SUBSTITUTED HETEROAROMATIC DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-6130232-A | Substituted piperidine derivatives as muscarinic M3 receptor antagonists | BANYU PHARMACEUTICAL COALTD (JP) | 2000-10-10 | — | — | US | disclosed |
| US-6040449-A | USEFUL FOR FORMING FLUORINE CONTAINING 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES, USEFUL AS ANTAGONIST FOR MUSCARINIC M3 RECEPTORS AND LESS SIDE EFFECT | BANYU PHARMACEUTICAL CO LTD (JP) | 2000-03-21 | — | — | US | disclosed |
| US-5948792-A | POTENT AND SELECTIVE ANTAGONISTS FOR MUSCARINIC M.SUB.3 RECEPTORS WITH LITTLE SIDE EFFECTS. | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-07 | — | — | US | disclosed |
| CN-1226888-A | Fluorinated 1,4-disubstituted piperidine derivatives | BANYU PHARMA CO LTD (JP) | 1999-08-25 | — | — | CN | disclosed |
| EP-0930298-A1 | FLUORINATED 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-07-21 | — | — | EP | disclosed |
| EP-0863141-A1 | SUBSTITUTED HETEROAROMATIC DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-09-09 | — | — | EP | disclosed |
| CN-1188471-A | 1,4-disubstituted piepridine derivatives | BANYU PHARMA CO LTD (JP) | 1998-07-22 | — | — | CN | disclosed |
| US-5750540-A | SIDE EFFECT REDUCTION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0823423-A1 | 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-02-11 | — | — | EP | disclosed |