Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16564364 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL16563690 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL16564352 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL28736805 | 0.82 | KMT2A (0.46) | SMN1; SMN2KMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL13141342 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL12727389 | 0.80 | ALDH1A1 (0.42) | SMN1; SMN2KMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL24614582 | 0.79 | SMN1; SMN2 (0.58) | SMN1; SMN2KMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL10316436 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL5582083 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL16714140 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2AMEN1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101815713-B | Polycyclic compounds | EISAI R&D MAN CO LTD | 2013-09-11 | — | — | CN | disclosed |