Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | AKT2 | P31751 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.41 |
| ▸ | PLG | P00747 | 2/20 | 0.38 |
| ▸ | KLK1 | P06870 | 2/20 | 0.38 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | SGK1 | O00141 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22400156 | 0.83 | HRH3 (0.48) | HRH3AKT2BACE1CD274TAAR1 | |
| SCHEMBL28807429 | 0.82 | MAOB (0.40) | BACE1CYP1A2CYP2A6 | |
| SCHEMBL3791657 | 0.81 | AKT2 (0.49) | HRH3AKT2BACE1CD274TAAR1 | |
| SCHEMBL21859425 | 0.79 | HRH3 (0.43) | HRH3AKT2BACE1CD274TAAR1 | |
| SCHEMBL17963054 | 0.79 | POLB (0.41) | — | |
| SCHEMBL3789670 | 0.78 | HRH3 (0.46) | HRH3AKT2BACE1CD274TAAR1 | |
| SCHEMBL21725464 | 0.77 | HRH3 (0.42) | HRH3AKT2BACE1CD274TAAR1 | |
| SCHEMBL27550928 | 0.77 | LMNA (0.43) | HRH3AKT2BACE1CD274TAAR1 | |
| SCHEMBL27872424 | 0.77 | HRH3 (0.42) | HRH3AKT2BACE1CD274TAAR1 | |
| SCHEMBL260102 | 0.75 | HRH3 (0.74) | HRH3AKT2BACE1TAAR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103570620-B | The luxuriant and rich with fragrance compounds of a kind of 1,12-imino group benzo [c], intermediate and preparation method and application | 昆山维信诺显示技术有限公司 | 2016-06-15 | — | — | CN | disclosed |
| CN-103570620-A | 1,12-iminobenzo[c]phenanthrene compound, intermediate, preparation method and application of compound | KUNSHAN VISIONOX DISPLAY TECH | 2014-02-12 | — | — | CN | disclosed |