Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.39 |
| ▸ | GMNN | O75496 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | APEX1 | P27695 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11609820 | 0.97 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL9210803 | 0.97 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL9214895 | 0.97 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL2287725 | 0.97 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL7391537 | 0.97 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL2723911 | 0.97 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL8714667 | 0.97 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL9211158 | 0.97 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL9202867 | 0.97 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL28289397 | 0.97 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103282435-B | Haze reduction in blends of aromatic-aliphatic polyesters with aliphatic polyesters and antimicrobial additives | EASTMAN CHEMICAL CO. (US) | 2016-04-20 | — | — | CN | disclosed |
| CN-103314045-B | The mist degree of the blend of aromatic-aliphatic polyester and antimicrobial additive reduces | EASTMAN CHEMICAL CO. (US) | 2016-02-03 | — | — | CN | disclosed |
| CN-103314045-A | Haze reduction for blends of aromatic-aliphatic polyesters and antimicrobial additives | EASTMAN CHEM CO | 2013-09-18 | — | — | CN | disclosed |
| CN-103282435-A | Haze reduction in blends of aromatic-aliphatic polyesters with aliphatic polyesters and antimicrobial additives | EASTMAN CHEM CO | 2013-09-04 | — | — | CN | disclosed |