Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | AKR1C3 | P42330 | 10/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | ME2 | P23368 | 6/20 | 0.58 |
| ▸ | ME1 | P48163 | 6/20 | 0.58 |
| ▸ | ME3 | Q16798 | 6/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3466014 | 0.86 | TDP1 (0.64) | TDP1LMNAKDM4EGAAMAPT | |
| SCHEMBL7041242 | 0.84 | MAPT (0.68) | TDP1LMNAKDM4EGAAMAPT | |
| SCHEMBL1128293 | 0.84 | GFER (0.71) | TDP1LMNAKDM4EGAAMAPT | |
| SCHEMBL19059406 | 0.84 | TDP1 (0.62) | TDP1LMNAKDM4EGAAMAPT | |
| SCHEMBL22627287 | 0.82 | LMNA (0.70) | TDP1LMNAKDM4EGAAMAPT | |
| SCHEMBL20696070 | 0.82 | GFER (0.69) | TDP1LMNAKDM4EGAAMAPT | |
| SCHEMBL27607283 | 0.82 | AKR1C3 (0.83) | LMNAKDM4EGAAAKR1C3ALDH1A1 | |
| SCHEMBL28806386 | 0.82 | GFER (0.73) | TDP1LMNAKDM4EGAAMAPT | |
| SCHEMBL27792690 | 0.81 | AKR1C3 (0.82) | LMNAMAPTAKR1C3ALDH1A1HTT | |
| SCHEMBL10981623 | 0.80 | ME2 (0.64) | TDP1LMNAKDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103313982-A | Phenyl-isoxazole derivatives and process for the preparation thereof | IL YANG PHARM CO LTD | 2013-09-18 | — | — | CN | claimed |
| CN-103313982-A | Phenyl-isoxazole derivatives and process for the preparation thereof | IL YANG PHARM CO LTD | 2013-09-18 | — | — | CN | disclosed |