Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 6/20 | 1.00 |
| ▸ | SLC1A1 | P43005 | 6/20 | 1.00 |
| ▸ | SLC1A3 | P43003 | 5/20 | 1.00 |
| ▸ | GRIK1 | P39086 | 12/20 | 0.69 |
| ▸ | GRIK2 | Q13002 | 12/20 | 0.69 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL71719 | 1.00 | SLC1A2 (1.00) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL7770487 | 1.00 | SLC1A2 (1.00) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL5284609 | 1.00 | SLC1A2 (1.00) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL30895 | 1.00 | SLC1A2 (1.00) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| Ethylene Glycol SCHEMBL28153823 | 0.94 | SLC1A1 (0.88) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| Glutamic Acid SCHEMBL1273613 | 0.87 | SLC1A2 (0.75) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL27467303 | 0.86 | SLC1A2 (0.76) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL20603228 | 0.86 | SLC1A2 (0.76) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL5324268 | 0.86 | SLC1A2 (0.76) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL751062 | 0.84 | SLC1A2 (0.71) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104093717-A | PAK inhibitors for the treatment of cell proliferative disorders | AFRAXIS INC | 2014-10-08 | — | — | CN | disclosed |
| CN-103596951-A | 8-ethyl-6-(aryl)pyrido [2,3-d]pyrimidin-7(8h)-ones for the treatment of nervous system disorders and cancer | AFRAXIS INC | 2014-02-19 | — | — | CN | disclosed |