Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL27937337

C=C(C)C(=O)c1ccsc1.C=C(C)C(=O)c1ccsc1.S

nearest known ligand 0.65

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.65
CES1 P23141 1/20 0.65
LCK P06239 1/20 0.52
FYN P06241 1/20 0.52
DAO P14920 1/20 0.52
HDAC1 Q13547 1/20 0.47
MAPT P10636 3/20 0.44
HPGD P15428 1/20 0.41
TDP1 Q9NUW8 2/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
THRA P10827 1/20 0.38
THRB P10828 1/20 0.38
HSD11B1 P28845 1/20 0.37
NPSR1 Q6W5P4 1/20 0.36
KCNK3 O14649 1/20 0.36
KCNK9 Q9NPC2 1/20 0.36
GPR52 Q9Y2T5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5069541 0.98 CES2 (0.68) CES2CES1LCKFYNDAO
SCHEMBL8182714 0.80 CES2 (1.00) CES2CES1LCKFYNDAO
SCHEMBL8198712 0.78
SCHEMBL10425 0.76
SCHEMBL5432309 0.76
Iodide SCHEMBL28995246 0.74 CES2 (0.62) CES2CES1LCKFYNDAO
SCHEMBL3957096 0.74 CES2 (0.77) CES2CES1LCKFYNDAO
SCHEMBL31465158 0.73 CES2 (0.50) CES2CES1LCKFYNDAO
SCHEMBL28670034 0.73 MAPT (0.71) CES2CES1MAPTKMT2AMEN1
SCHEMBL4771811 0.72 CES2 (0.74) CES2CES1LCKFYNDAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103320146-B The manufacture method of crystal aligning agent, liquid crystal orienting film, liquid crystal display device and liquid crystal display device JSR株式会社 2016-06-15 CN disclosed
CN-103320146-A Liquid crystal aligning agent, liquid crystal aligning film, liquid crystal display element and method of making liquid crystal display element JSR CORP 2013-09-25 CN disclosed