Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 11/20 | 0.41 |
| ▸ | IKBKB | O14920 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 5/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.37 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29831600 | 0.91 | PDE5A (0.62) | PDE5AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL2680351 | 0.91 | PDE5A (0.62) | PDE5AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL300373 | 0.91 | PDE5A (0.62) | PDE5AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL26647596 | 0.84 | PDE5A (0.58) | PDE5AIKBKBPPARGKDM4EALDH1A1 | |
| SCHEMBL28020392 | 0.84 | AURKA (0.48) | PDE5AALDH1A1 | |
| SCHEMBL15546782 | 0.83 | PDE5A (0.48) | PDE5AIKBKBMEN1ALDH1A1KMT2A | |
| SCHEMBL20559971 | 0.83 | PDE5A (0.42) | PDE5AALDH1A1 | |
| SCHEMBL27950930 | 0.83 | PDE5A (0.61) | PDE5AKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL27937575 | 0.82 | PDE5A (0.60) | PDE5AIKBKBKDM4EMEN1ALDH1A1 | |
| SCHEMBL290380 | 0.82 | PDE5A (0.56) | PDE5APPARAKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103547267-A | Treatment of addiction and impulse control disorders using PDE7 inhibitors | OMEROS CORP | 2014-01-29 | — | — | CN | disclosed |