Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 3/20 | 0.48 |
| ▸ | PDE5A | O76074 | 2/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.45 |
| ▸ | HRH1 | P35367 | 3/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290626 | 0.90 | PDE5A (0.60) | AURKAPDE5AALDH1A1HPGD | |
| SCHEMBL29832171 | 0.90 | PDE5A (0.60) | AURKAPDE5AALDH1A1HPGD | |
| SCHEMBL15546782 | 0.90 | PDE5A (0.48) | AURKAPDE5AHRH4HRH3ALDH1A1 | |
| SCHEMBL20559971 | 0.88 | PDE5A (0.42) | AURKAPDE5ACHEK1ALDH1A1HPGD | |
| SCHEMBL299322 | 0.88 | PDE5A (0.57) | AURKAPDE5AALDH1A1HPGD | |
| SCHEMBL26647638 | 0.87 | PDE5A (0.57) | AURKAPDE5AALDH1A1HPGD | |
| SCHEMBL27937609 | 0.84 | PDE5A (0.48) | PDE5AALDH1A1 | |
| SCHEMBL26647596 | 0.84 | PDE5A (0.58) | PDE5AALDH1A1HPGD | |
| SCHEMBL291205 | 0.83 | PDE5A (0.56) | AURKAPDE5AHRH4HRH3 | |
| SCHEMBL27950930 | 0.82 | PDE5A (0.61) | AURKAPDE5AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104768556-A | Treatment of addiction and impulse control disorders using PDE7 inhibitors | OMEROS CORP | 2015-07-08 | — | — | CN | disclosed |