Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 9/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 5-Bromosalicylaldehyde SCHEMBL29399181 | 0.86 | ERN1 (1.00) | ERN1KDM4EKMT2AGAAMAPT | |
| 5-Bromosalicylaldehyde SCHEMBL79219 | 0.86 | ERN1 (1.00) | ERN1KDM4EKMT2AGAAMAPT | |
| 5-Bromosalicylaldehyde SCHEMBL7633780 | 0.84 | ERN1 (0.88) | ERN1KDM4EKMT2AGAAMAPT | |
| 5-Bromosalicylaldehyde SCHEMBL28337235 | 0.84 | ERN1 (0.96) | ERN1KDM4EKMT2AGAAMAPT | |
| 5-Bromosalicylaldehyde SCHEMBL28108942 | 0.82 | ERN1 (0.92) | ERN1KDM4EKMT2AGAAMAPT | |
| 5-Bromosalicylaldehyde SCHEMBL28103357 | 0.81 | ERN1 (0.81) | ERN1KDM4EKMT2AGAAMAPT | |
| 5-Bromosalicylaldehyde SCHEMBL27802349 | 0.81 | ERN1 (0.81) | ERN1KDM4EKMT2AGAAMAPT | |
| 5-Bromosalicylaldehyde SCHEMBL29175395 | 0.80 | ERN1 (0.73) | ERN1KDM4EKMT2AGAAMAPT | |
| 5-Bromosalicylaldehyde SCHEMBL28150995 | 0.77 | ERN1 (0.81) | ERN1KDM4EKMT2AGAAMAPT | |
| SCHEMBL27923095 | 0.77 | ERN1 (0.73) | ERN1KDM4EKMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103553975-A | 5-bromo salicylaldehyde carbohydrazide bis-schiff base and synthesis method | UNIV GUILIN TECH GUT | 2014-02-05 | — | — | CN | disclosed |
| CN-103553975-A | 5-bromo salicylaldehyde carbohydrazide bis-schiff base and synthesis method | UNIV GUILIN TECH GUT | 2014-02-05 | — | — | CN | disclosed |