Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 10/20 | 0.88 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 5-Bromosalicylaldehyde SCHEMBL28108942 | 0.94 | ERN1 (0.92) | ERN1CA12CA9KDM4EKMT2A | |
| 5-Bromosalicylaldehyde SCHEMBL79219 | 0.94 | ERN1 (1.00) | ERN1CA12CA9KDM4EKMT2A | |
| 5-Bromosalicylaldehyde SCHEMBL29399181 | 0.94 | ERN1 (1.00) | ERN1CA12CA9KDM4EKMT2A | |
| 5-Bromosalicylaldehyde SCHEMBL28337235 | 0.92 | ERN1 (0.96) | ERN1CA12CA9KDM4EKMT2A | |
| 5-Bromosalicylaldehyde SCHEMBL27802349 | 0.89 | ERN1 (0.81) | ERN1CA12CA9KDM4EKMT2A | |
| 5-Bromosalicylaldehyde SCHEMBL28103357 | 0.89 | ERN1 (0.81) | ERN1CA12CA9KDM4EKMT2A | |
| 5-Bromosalicylaldehyde SCHEMBL28150995 | 0.89 | ERN1 (0.81) | ERN1CA12CA9KDM4EKMT2A | |
| 5-Bromosalicylaldehyde SCHEMBL29175395 | 0.84 | ERN1 (0.73) | ERN1CA12CA9KDM4EKMT2A | |
| 5-Bromosalicylaldehyde SCHEMBL27938580 | 0.84 | ERN1 (0.73) | ERN1CA12CA9KDM4EKMT2A | |
| 5-Bromosalicylaldehyde SCHEMBL28005058 | 0.84 | ERN1 (0.67) | ERN1CA12CA9KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194514-A1 | METAL COMPLEXES OF TRIPODAL LIGANDS | Ciba SC Holding AG (CH) | 2002-04-10 | — | — | EP | disclosed |
| WO-2001005925-A1 | METAL COMPLEXES OF TRIPODAL LIGANDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-01-25 | — | — | WO | disclosed |