Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.43 |
| ▸ | GCG | P01275 | 2/20 | 0.42 |
| ▸ | GCGR | P47871 | 11/20 | 0.41 |
| ▸ | GIPR | P48546 | 3/20 | 0.41 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.41 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.41 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.41 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.41 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.41 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.41 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.41 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.41 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9101175 | 0.90 | PTPN1 (0.45) | PTPN1DGAT1S1PR3GCGGCGR | |
| SCHEMBL28807635 | 0.88 | PTPN1 (0.48) | PTPN1S1PR3KMT2AFFAR1S1PR1 | |
| SCHEMBL27942821 | 0.81 | PTPN1 (0.47) | PTPN1S1PR3KMT2AS1PR1 | |
| SCHEMBL9103709 | 0.80 | S1PR1 (0.55) | PTPN1S1PR3FFAR1S1PR1 | |
| SCHEMBL27920250 | 0.79 | PTPN1 (0.44) | PTPN1S1PR3KMT2AS1PR1 | |
| SCHEMBL27938780 | 0.78 | PTPN1 (0.48) | PTPN1FFAR1S1PR1 | |
| SCHEMBL27942984 | 0.78 | S1PR1 (0.54) | S1PR3S1PR1 | |
| SCHEMBL27938890 | 0.77 | PTPN1 (0.49) | PTPN1S1PR3FFAR1S1PR1 | |
| SCHEMBL27920264 | 0.76 | PTPN1 (0.46) | PTPN1FFAR1S1PR1 | |
| SCHEMBL27938944 | 0.75 | TP53 (0.47) | PTPN1S1PR3KMT2AFFAR1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103338766-A | Oxadiazole derivatives as sphingosine 1-phosphate (S1P) receptor modulators | ALLERGAN INC | 2013-10-02 | — | — | CN | claimed |
| CN-103338766-A | Oxadiazole derivatives as sphingosine 1-phosphate (S1P) receptor modulators | ALLERGAN INC | 2013-10-02 | — | — | CN | disclosed |