Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9103709 | 0.92 | S1PR1 (0.55) | PTPN1S1PR1FFAR1S1PR3S1PR4 | |
| SCHEMBL27938780 | 0.90 | PTPN1 (0.48) | PTPN1S1PR1FFAR1HDAC1HDAC8 | |
| SCHEMBL27938890 | 0.90 | PTPN1 (0.49) | PTPN1S1PR1FFAR1S1PR3TP53 | |
| SCHEMBL27920250 | 0.89 | PTPN1 (0.44) | PTPN1S1PR1S1PR3KMT2AS1PR4 | |
| SCHEMBL27938775 | 0.88 | PTPN1 (0.44) | PTPN1S1PR1FFAR1S1PR3KMT2A | |
| SCHEMBL27920264 | 0.88 | PTPN1 (0.46) | PTPN1S1PR1FFAR1HDAC1HDAC8 | |
| SCHEMBL27938944 | 0.87 | TP53 (0.47) | PTPN1S1PR1FFAR1S1PR3KMT2A | |
| SCHEMBL28805778 | 0.85 | PTPN1 (0.47) | PTPN1S1PR1FFAR1TP53HDAC1 | |
| SCHEMBL9100995 | 0.84 | PTPN1 (0.47) | PTPN1S1PR1FFAR1TP53HDAC1 | |
| SCHEMBL9101572 | 0.83 | FFAR1 (0.50) | PTPN1S1PR1FFAR1S1PR3TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103338766-A | Oxadiazole derivatives as sphingosine 1-phosphate (S1P) receptor modulators | ALLERGAN INC | 2013-10-02 | — | — | CN | claimed |