⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30267514 | 0.74 | — | — | |
| SCHEMBL3823910 | 0.74 | — | — | |
| SCHEMBL131702 | 0.67 | — | — | |
| Water SCHEMBL7137776 | 0.65 | TAAR1 (0.53) | — | |
| Ammonia Solution, Strong SCHEMBL30638599 | 0.65 | — | — | |
| Ammonia Solution, Strong SCHEMBL30638598 | 0.65 | — | — | |
| Iodide SCHEMBL633203 | 0.65 | — | — | |
| Iodide SCHEMBL28564958 | 0.65 | — | — | |
| Water SCHEMBL29051398 | 0.65 | — | — | |
| SCHEMBL28550216 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103608346-B | As the 7-naphthyridine derivatives of hypoxia inducible factor (HIF) hydroxylase inhibitors | 菲布罗根有限公司 | 2016-06-15 | — | — | CN | disclosed |
| CN-103608346-A | Naphthyridine derivatives as inhibitors of hypoxia inducible factor (HIF) hydroxylase | FIBROGEN INC | 2014-02-26 | — | — | CN | disclosed |