⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6043119 | 0.86 | — | — | |
| SCHEMBL9020634 | 0.86 | BRD4 (0.39) | — | |
| SCHEMBL12871698 | 0.67 | — | — | |
| SCHEMBL9020643 | 0.67 | — | — | |
| Ethylene SCHEMBL28733226 | 0.65 | KDM4E (0.32) | — | |
| SCHEMBL44131 | 0.64 | — | — | |
| SCHEMBL213996 | 0.62 | — | — | |
| SCHEMBL2216577 | 0.62 | — | — | |
| SCHEMBL7773407 | 0.62 | — | — | |
| SCHEMBL1098651 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1045 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348516-A1 | YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | MOLECURE S.A. (PL) | 2023-11-02 | — | — | US | claimed |
| EP-4269400-A1 | YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | Molecure SA (PL) | 2023-11-01 | — | — | EP | claimed |
| US-20230278996-A1 | YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | MOLECURE S.A. (PL) | 2023-09-07 | — | — | US | claimed |
| EP-3077354-B1 | NOVEL METHOD FOR THE SYNTHESIS OF AGOMELATINE | SERVIER LAB (FR) | 2017-11-29 | — | — | EP | claimed |
| US-9604911-B2 | Process for the synthesis of agomelatine | LES LABORATOIRES SERVIER (FR) | 2017-03-28 | — | — | US | claimed |
| US-20160368859-A1 | PROCESS FOR THE SYNTHESIS OF AGOMELATINE | LES LABORATOIRES SERVIER (FR) | 2016-12-22 | — | — | US | claimed |
| EP-1514542-B1 | Medicinal composition comprising Tacrine or Donepezil for improving brain function. | TOYAMA CHEMICAL CO LTD (JP) | 2012-02-22 | — | — | EP | claimed |
| US-20110245242-A1 | Heterocyclically Substituted Anilinopyrimides | BAYER CROPSCIENCE AG (DE) | 2011-10-06 | — | — | US | claimed |
| US-20100069244-A1 | Pyridine Compounds for Combating Pests | BASF SE (DE) | 2010-03-18 | — | — | US | claimed |
| CN-101568258-A | Pyridine derivatives for combating pests | BASF SE (DE) | 2009-10-28 | — | — | CN | claimed |
| US-4024152-A | 4-Dithio-3-imido-azetidin-2-ones | ELI LILLY AND COMPANY (US) | 1977-05-17 | — | — | US | claimed |
| US-4014873-A | Process for the production of 7-acylamidocephalosporins | MERCK & CO., INC. (US) | 1977-03-29 | — | — | US | claimed |
| US-4008230-A | Process for preparing 3-hydroxy cephalosporins | ELI LILLY AND COMPANY (US) | 1977-02-15 | — | — | US | claimed |
| US-3968108-A | Process for preparing a desacetoxycephalosporin from a penam and/or a cepham compound | ELI LILLY AND COMPANY (US) | 1976-07-06 | — | — | US | claimed |
| US-3962226-A | 3-NITROOXYCEPHAM COMPOUNDS AND PROCESS FOR PREPARING DESACETOXYCEPHALOSPORINS THEREFROM | ELI LILLY AND COMPANY (US) | 1976-06-08 | — | — | US | claimed |
| US-3962276-A | ENZYME INHIBITORS | ELI LILLY AND COMPANY (US) | 1976-06-08 | — | — | US | claimed |
| US-3960851-A | Preparation of desacetoxy-cephalosporin sulfoxides from penicillin sulfoxides | ELI LILLY AND COMPANY (US) | 1976-06-01 | — | — | US | claimed |
| US-3944545-A | Process for preparing desacetoxycephalosporins | ELI LILLY AND COMPANY (US) | 1976-03-16 | — | — | US | claimed |
| US-3932387-A | Process for the conversion of 3-methyl-3-hydroxycepham compounds | ELI LILLY AND COMPANY (US) | 1976-01-13 | — | — | US | claimed |
| US-3932391-A | Cephalosporin isocyanates | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-01-13 | — | — | US | claimed |