Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 5/20 | 0.43 |
| ▸ | ABAT | P80404 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28444643 | 0.79 | ABAT (0.43) | LOXL2ABATHRH3NOS3NOS1 | |
| SCHEMBL18106924 | 0.78 | MAPT (0.46) | KIF11ESR1ESR2 | |
| SCHEMBL28049734 | 0.78 | ESR1 (0.58) | KIF11ESR1ESR2SMN1; SMN2 | |
| SCHEMBL2689524 | 0.77 | LOXL2 (0.44) | LOXL2ABATHRH3MAOBNOS3 | |
| Hydrochloric Acid SCHEMBL6463385 | 0.77 | ESR1 (0.56) | KIF11ESR1ESR2 | |
| SCHEMBL5085651 | 0.76 | KCNN4 (0.46) | KIF11TAAR1KDM4ESMN1; SMN2 | |
| SCHEMBL4825874 | 0.76 | ABAT (0.48) | LOXL2ABATHRH3MAOBNOS3 | |
| SCHEMBL42067 | 0.76 | KCNN4 (0.46) | KIF11TAAR1KDM4ESMN1; SMN2 | |
| SCHEMBL28065526 | 0.76 | KCNN4 (0.46) | KIF11TAAR1KDM4ESMN1; SMN2 | |
| SCHEMBL19941702 | 0.75 | MAOB (0.43) | LOXL2ABATHRH3MAOBNOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103588906-A | Preparation method for 1-(4-methylphenyl)-1-propanol substituted 6-amino-beta-cyclodextrin derivative | SHANGHAI RUICHUANG MEDICAL TECHNOLOGY CO LTD | 2014-02-19 | — | — | CN | disclosed |