Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31530800 | 0.80 | PDE10A (0.37) | PDE10AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL31295234 | 0.78 | PDE10A (0.42) | PDE10AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL27816947 | 0.78 | GGPS1 (0.48) | ALDH1A1KDM4EMAPTHPGDRAB9A | |
| SCHEMBL9384535 | 0.76 | TBXAS1 (0.55) | PDE10AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL3798563 | 0.72 | KDM4E (0.47) | PDE10AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL24090159 | 0.72 | KDM4E (0.50) | PDE10AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL10272042 | 0.72 | KDM4E (0.50) | PDE10AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL25243301 | 0.72 | PDE10A (0.46) | PDE10AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL24090169 | 0.71 | KDM4E (0.49) | PDE10AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL20864246 | 0.69 | KDM4E (0.50) | PDE10AALDH1A1KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103373996-A | Bicyclic derivatives serving as CRTH2 receptor antagonist | Shandong henry medical science and technology co ltd | 2013-10-30 | — | — | CN | disclosed |