Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 5/20 | 0.47 |
| ▸ | JAK2 | O60674 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | CHUK | O15111 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5616609 | 0.91 | TTR (0.49) | IKBKBJAK2MEN1EIF2AK2KMT2A | |
| SCHEMBL28202986 | 0.89 | IKBKB (0.47) | IKBKBJAK2MEN1EIF2AK2KMT2A | |
| SCHEMBL28186096 | 0.88 | IKBKB (0.42) | IKBKBJAK2MEN1EIF2AK2KMT2A | |
| SCHEMBL30370009 | 0.84 | BCAT2 (0.57) | IKBKBKEAP1NFE2L2CHUKPARP1 | |
| SCHEMBL27940758 | 0.82 | PARP1 (0.46) | IKBKBJAK2MEN1EIF2AK2KMT2A | |
| SCHEMBL28202981 | 0.82 | TSHR (0.42) | IKBKBJAK2MEN1EIF2AK2KMT2A | |
| SCHEMBL27704997 | 0.82 | BCAT2 (0.59) | IKBKBKEAP1NFE2L2PARP1BCAT2 | |
| SCHEMBL9746985 | 0.82 | PARP1 (0.51) | IKBKBTDP1KEAP1NFE2L2CYP3A4 | |
| SCHEMBL27214460 | 0.81 | BCAT2 (0.63) | IKBKBJAK2TDP1KEAP1NFE2L2 | |
| SCHEMBL27940776 | 0.81 | PARP1 (0.53) | JAK2KEAP1NFE2L2PARP1BCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103373939-A | 4-methoxy-N, N'-bisubstituted phenyl-1, 3-benzene diamide compounds as well as preparation method and application thereof | UNIV TIANJIN TECHNOLOGY | 2013-10-30 | — | — | CN | claimed |
| CN-103373939-A | 4-methoxy-N, N'-bisubstituted phenyl-1, 3-benzene diamide compounds as well as preparation method and application thereof | UNIV TIANJIN TECHNOLOGY | 2013-10-30 | — | — | CN | disclosed |