SCHEMBL27940977

SCHEMBL27940977

CCC(C)n1cnc(C(C)(C)CC)c1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM5A P29375 1/20 0.31
ADORA2A P29274 1/20 0.30
ADORA2B P29275 1/20 0.30
ADORA1 P30542 1/20 0.30
HMGCR P04035 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27941024 0.87 HMGCR (0.31) KDM5AHMGCR
SCHEMBL27922401 0.87 ACHE (0.33)
SCHEMBL18250318 0.86 KDM5A (0.32) KDM5AADORA2AADORA2BADORA1
SCHEMBL27922449 0.86 KDM5A (0.32) KDM5AHMGCR
SCHEMBL27832088 0.83 CNR2 (0.31)
SCHEMBL27940968 0.83 HMGCR (0.30) HMGCR
SCHEMBL14421034 0.83 KDM5A (0.33) KDM5AADORA2AADORA2BADORA1
SCHEMBL27922422 0.76 ACHE (0.32) HMGCR
SCHEMBL18250313 0.72 ACHE (0.34)
SCHEMBL28807924 0.72 HMGCR (0.32) KDM5AHMGCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103361630-A Group 2 imidazolate formulations for direct liquid injection AIR PROD & CHEM 2013-10-23 CN disclosed