Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 12/20 | 0.78 |
| ▸ | ESR2 | Q92731 | 12/20 | 0.78 |
| ▸ | APP | P05067 | 2/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.50 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3928011 | 0.88 | ESR1 (1.00) | ESR1ESR2APPCYP1A1CYP1A2 | |
| SCHEMBL1428881 | 0.85 | ESR1 (0.56) | ESR1ESR2CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL29978577 | 0.73 | ABCB1 (0.82) | FLT3MKNK2IP6K2CYP1A1CYP1A2 | |
| SCHEMBL311530 | 0.73 | ABCB1 (0.82) | FLT3MKNK2IP6K2CYP1A1CYP1A2 | |
| SCHEMBL18274896 | 0.73 | ESR1 (0.53) | ESR1ESR2APPCYP1A1CYP1A2 | |
| SCHEMBL7818271 | 0.73 | ESR1 (0.60) | ESR1ESR2APPCYP1B1KDM4E | |
| SCHEMBL4008387 | 0.73 | EGFR (0.50) | ESR1ESR2APPCYP1A1CYP1A2 | |
| SCHEMBL3927970 | 0.72 | ALDH1A1 (0.48) | ESR1ESR2APPCYP1A1CYP1A2 | |
| SCHEMBL18224199 | 0.72 | FASN (0.69) | ESR1ESR2APPCYP1A1CYP1A2 | |
| SCHEMBL12549065 | 0.72 | ABL1 (0.62) | ESR1ESR2APPCYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103373974-B | Preparation method of 2-(4-hydroxyphenyl)-5,7-dimethoxy benzofuran | CAS GUANGZHOU CHEMISTRY CO LTD | 2015-02-04 | — | — | CN | claimed |
| CN-103373974-B | Preparation method of 2-(4-hydroxyphenyl)-5,7-dimethoxy benzofuran | CAS GUANGZHOU CHEMISTRY CO LTD | 2015-02-04 | — | — | CN | disclosed |
| CN-103373974-B | Preparation method of 2-(4-hydroxyphenyl)-5,7-dimethoxy benzofuran | CAS GUANGZHOU CHEMISTRY CO LTD | 2015-02-04 | — | — | CN | disclosed |
| CN-103373974-B | Preparation method of 2-(4-hydroxyphenyl)-5,7-dimethoxy benzofuran | CAS GUANGZHOU CHEMISTRY CO LTD | 2015-02-04 | — | — | CN | disclosed |
| CN-103373974-A | Preparation method of 2-(4-hydroxyphenyl)-5,7-dimethoxy benzofuran | CAS GUANGZHOU CHEMISTRY CO LTD | 2013-10-30 | — | — | CN | disclosed |
| CN-103373974-A | Preparation method of 2-(4-hydroxyphenyl)-5,7-dimethoxy benzofuran | CAS GUANGZHOU CHEMISTRY CO LTD | 2013-10-30 | — | — | CN | disclosed |