Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10044606 | 0.80 | CYP1A2 (0.44) | HSD17B10ALDH1A1USP2CYP3A4MAPK1 | |
| SCHEMBL3326056 | 0.80 | HSD17B10 (0.61) | HSD17B10KDM4EABL1POLBMAPT | |
| SCHEMBL349193 | 0.80 | HSD17B10 (0.61) | HSD17B10KDM4EABL1POLBMAPT | |
| SCHEMBL4395434 | 0.80 | HSD17B10 (0.61) | HSD17B10KDM4EABL1POLBMAPT | |
| SCHEMBL12404016 | 0.79 | PDE4A (0.47) | HSD17B10ALDH1A1USP2CYP3A4MAPK1 | |
| SCHEMBL4394914 | 0.78 | HSD17B10 (0.44) | HSD17B10KDM4EABL1POLBMAPT | |
| SCHEMBL3927410 | 0.78 | HSD17B10 (0.54) | HSD17B10KDM4EABL1POLBMAPT | |
| SCHEMBL9377735 | 0.77 | CYP1A2 (0.44) | ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL1599400 | 0.77 | HSD17B10 (0.56) | HSD17B10KDM4EABL1POLBMAPT | |
| SCHEMBL21526724 | 0.76 | CYP1A2 (0.45) | HSD17B10USP2CYP3A4MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103373974-A | Preparation method of 2-(4-hydroxyphenyl)-5,7-dimethoxy benzofuran | CAS GUANGZHOU CHEMISTRY CO LTD | 2013-10-30 | — | — | CN | claimed |
| CN-103373974-A | Preparation method of 2-(4-hydroxyphenyl)-5,7-dimethoxy benzofuran | CAS GUANGZHOU CHEMISTRY CO LTD | 2013-10-30 | — | — | CN | disclosed |