Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12404016 | 0.85 | PDE4A (0.47) | CYP1A2TAAR1ADRA1AHSD17B10PDE4A | |
| SCHEMBL29153638 | 0.84 | CYP1A2 (0.46) | CYP1A2TAAR1ADRA1AAPLNRHTR2A | |
| SCHEMBL9377735 | 0.79 | CYP1A2 (0.44) | CYP1A2TAAR1ADRA1AAPLNRHTR2A | |
| SCHEMBL10044606 | 0.79 | CYP1A2 (0.44) | CYP1A2TAAR1ADRA1AHSD17B10APLNR | |
| SCHEMBL8472752 | 0.79 | CYP1A2 (0.49) | CYP1A2CYP2D6TAAR1ADRA1AHSD17B10 | |
| SCHEMBL27785360 | 0.78 | CYP1A2 (0.41) | CYP1A2TAAR1ADRA1AHSD17B10APLNR | |
| SCHEMBL3395789 | 0.78 | CYP1A2 (0.43) | CYP1A2TAAR1ADRA1AHSD17B10APLNR | |
| SCHEMBL27942158 | 0.76 | HSD17B10 (0.61) | CYP1A2HSD17B10USP2CYP3A4MAPK1 | |
| SCHEMBL1203850 | 0.76 | ALDH1A1 (0.53) | CYP1A2CYP2D6CA12CA1CA2 | |
| SCHEMBL8354454 | 0.75 | PDE4A (0.44) | CYP1A2TAAR1ADRA1AHSD17B10PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10640469-B2 | Polyhydroxyphthalazinone compound, preparation method thereof and use thereof | REJUVGEN PHARMACEUTICALS, INC. (CN) | 2020-05-05 | — | — | US | disclosed |
| EP-3564215-A1 | POLYHYDROXYPHTHALAZINONE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Rejuvgen Pharmaceuticals, Inc. (CN) | 2019-11-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10640469-B2 | Polyhydroxyphthalazinone compound, preparation method thereof and use thereof | ESRRB, ESR2, ESRRA | CYP1A2 138/4885CYP2D6 181/4885TAAR1 1357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.