SCHEMBL27942166

SCHEMBL27942166

CCCC(Oc1cc(C)c(-n2cc3ccccc3n2)c(C)c1)c1ccc(NCCC(=O)O)cc1

nearest known ligand 0.79

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GCG P01275 16/20 0.79
GCGR P47871 5/20 0.61
CHRM5 P08912 1/20 0.54
GLP1R P43220 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11899686 0.89 GCG (1.00) GCGGCGRCHRM5GLP1R
SCHEMBL11899682 0.89 GCG (1.00) GCGGCGRCHRM5GLP1R
SCHEMBL28807986 0.81 GCG (0.79) GCGGCGRCHRM5GLP1R
SCHEMBL12471641 0.81 GCGR (0.81) GCGGCGRCHRM5GLP1R
SCHEMBL11899422 0.80 GCG (1.00) GCGGCGRCHRM5GLP1R
SCHEMBL28805997 0.79 GCG (0.80) GCGGCGRCHRM5GLP1R
SCHEMBL11900878 0.76 GCG (1.00) GCGGCGR
SCHEMBL16291345 0.75 GCG (0.58) GCGGCGRCHRM5GLP1R
SCHEMBL27922854 0.75 GCG (0.58) GCGGCGRCHRM5GLP1R
SCHEMBL11899863 0.73 GCG (0.87) GCGGCGRCHRM5GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103370306-A Glucagon receptor modulators PFIZER 2013-10-23 CN disclosed