Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | CPT2 | P23786 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ACLY | P53396 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3137659 | 0.84 | ALDH1A1 (0.36) | HMGCRCHRM1TBXA2RADRA1AGAA | |
| SCHEMBL11523073 | 0.79 | GAA (0.46) | HMGCRCHRM1TBXA2RADRA1AGAA | |
| T-Butylacetic Acid SCHEMBL15106943 | 0.78 | HMGCR (0.42) | HMGCRCHRM1TBXA2RADRA1AGAA | |
| SCHEMBL2963340 | 0.77 | HMGCR (0.46) | HMGCRCHRM1TBXA2RADRA1AGAA | |
| SCHEMBL284431 | 0.75 | CYP2C19 (0.42) | HMGCRCHRM1TBXA2RADRA1AGAA | |
| SCHEMBL5323393 | 0.73 | HMGCR (0.42) | HMGCRCHRM1TBXA2RADRA1AGAA | |
| Acetic Acid SCHEMBL15573268 | 0.73 | CYP2C19 (0.41) | HMGCRCHRM1TBXA2RADRA1AGAA | |
| SCHEMBL21048439 | 0.73 | CYP2C19 (0.41) | HMGCRCHRM1TBXA2RADRA1AGAA | |
| Acetone SCHEMBL9653544 | 0.73 | CYP2C19 (0.41) | HMGCRCHRM1TBXA2RADRA1AGAA | |
| SCHEMBL597227 | 0.73 | CYP2C19 (0.41) | HMGCRCHRM1TBXA2RADRA1AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103360405-B | A kind of spirocyclic compound 2,4,8,10-tetra-carbonyl-3,9-dioxa volution [5,5] undecanoic synthetic method | WUHAN INSTITUTE OF TECHNOLOGY (CN) | 2015-09-09 | — | — | CN | claimed |
| CN-103288845-B | Spiro-compound 2,4,8,10-tetracarbonyl-3,9-dioxaspiro[5,5] hendecane and synthetic method thereof | WUHAN INST TECHNOLOGY | 2015-05-20 | — | — | CN | claimed |
| CN-103274924-B | Compound 1,3-dicarboxyl-2,2-bis(carbethoxy)propane and synthesis method thereof | WUHAN INSTITUTE OF TECHNOLOGY (CN) | 2014-10-15 | — | — | CN | claimed |
| CN-103333322-B | A kind of spirocyclic compound is at the application method of epoxy-resin systems | WUHAN INSTITUTE OF TECHNOLOGY (CN) | 2016-02-24 | — | — | CN | disclosed |
| CN-103275109-B | A kind of compound 1,3-dibrominated magnesium-2,2-bis-(magnesium bromide methyl) propane and preparation method thereof | WUHAN INSTITUTE OF TECHNOLOGY (CN) | 2015-09-09 | — | — | CN | disclosed |
| CN-103360405-B | A kind of spirocyclic compound 2,4,8,10-tetra-carbonyl-3,9-dioxa volution [5,5] undecanoic synthetic method | WUHAN INSTITUTE OF TECHNOLOGY (CN) | 2015-09-09 | — | — | CN | disclosed |
| CN-103288845-B | Spiro-compound 2,4,8,10-tetracarbonyl-3,9-dioxaspiro[5,5] hendecane and synthetic method thereof | WUHAN INST TECHNOLOGY | 2015-05-20 | — | — | CN | disclosed |
| CN-103274924-B | Compound 1,3-dicarboxyl-2,2-bis(carbethoxy)propane and synthesis method thereof | WUHAN INSTITUTE OF TECHNOLOGY (CN) | 2014-10-15 | — | — | CN | disclosed |
| CN-103360405-A | Synthesis method of spiro-compound 2,4,8,10-tetracarbonyl-3,9-dioxaspiro[5,5]undecane | WUHAN INST TECHNOLOGY | 2013-10-23 | — | — | CN | disclosed |