Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | TBXAS1 | P24557 | 12/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957742 | 0.77 | AKR1C3 (0.63) | AKR1C3TBXAS1 | |
| SCHEMBL7957744 | 0.77 | AKR1C3 (0.63) | AKR1C3TBXAS1 | |
| SCHEMBL3629527 | 0.76 | AKR1C3 (0.52) | AKR1C3TBXAS1APEX1RXRARXRB | |
| SCHEMBL3629524 | 0.76 | AKR1C3 (0.52) | AKR1C3TBXAS1APEX1RXRARXRB | |
| SCHEMBL27224536 | 0.75 | AKR1C3 (0.67) | AKR1C3TBXAS1HTT | |
| SCHEMBL7963228 | 0.75 | AKR1C3 (0.67) | AKR1C3TBXAS1HTT | |
| SCHEMBL7268646 | 0.75 | AKR1C3 (0.67) | AKR1C3TBXAS1HTT | |
| SCHEMBL8746655 | 0.75 | AKR1C3 (0.67) | AKR1C3TBXAS1APEX1HTT | |
| SCHEMBL8746653 | 0.75 | AKR1C3 (0.67) | AKR1C3TBXAS1APEX1HTT | |
| SCHEMBL2462983 | 0.75 | AKR1C3 (0.82) | AKR1C3TBXAS1APEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104478812-A | Pyrimidone compound for treating Lp-PLA2-mediated diseases or illness | GLAXO GROUP LTD | 2015-04-01 | — | — | CN | disclosed |
| CN-103347864-A | For treating diseases caused by Lp-PLA2Pyrimidone compounds for mediated diseases or conditions | GLAXO GROUP LTD | 2013-10-09 | — | — | CN | disclosed |