SCHEMBL7963228

SCHEMBL7963228

C/C(=C\c1ccncc1)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.67
TBXAS1 P24557 10/20 0.53
CYP19A1 P11511 1/20 0.47
CYP11B2 P19099 1/20 0.47
JUN P05412 1/20 0.45
NFKB1 P19838 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
KDM4E B2RXH2 1/20 0.44
HTT P42858 2/20 0.42
NAPRT Q6XQN6 1/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
STAT1 P42224 1/20 0.41
MITF O75030 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27224536 1.00 AKR1C3 (0.67) AKR1C3TBXAS1CYP19A1CYP11B2JUN
SCHEMBL7268646 1.00 AKR1C3 (0.67) AKR1C3TBXAS1CYP19A1CYP11B2JUN
SCHEMBL11061416 0.84 TBXAS1 (0.70) AKR1C3TBXAS1CYP11B2
SCHEMBL10983292 0.84 AKR1C3 (0.53) AKR1C3TBXAS1CYP1A2CYP3A4CYP2D6
SCHEMBL10983294 0.84 AKR1C3 (0.53) AKR1C3TBXAS1CYP1A2CYP3A4CYP2D6
SCHEMBL11061432 0.84 TBXAS1 (0.70) AKR1C3TBXAS1CYP11B2
SCHEMBL2462983 0.84 AKR1C3 (0.82) AKR1C3TBXAS1KDM4EHTT
SCHEMBL2462984 0.84 AKR1C3 (0.82) AKR1C3TBXAS1KDM4EHTT
Hydrochloric Acid SCHEMBL11067847 0.83 TBXAS1 (0.72) AKR1C3TBXAS1
Hydrochloric Acid SCHEMBL10989978 0.83 AKR1C3 (0.51) AKR1C3TBXAS1CYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240217932-A1 PYRIDIUM ESTERS THE PROCTER AND GAMBLE COMPANY 2024-07-04 US disclosed
EP-4374698-A1 PYRIDINIUM ESTERS The Procter & Gamble Company (US) 2024-05-29 EP disclosed
WO-2001007409-A1 CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS ASTRAZENECA UK LIMITED (GB) 2001-02-01 WO disclosed
US-5177096-A Angiotensin II receptor antagonist SMITHKLINE BEECHAM CORPORATION (US) 1993-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240217932-A1 PYRIDIUM ESTERS C5, CBR3, CHRM1 AKR1C3 40/4885TBXAS1 1042/4885CYP19A1 782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.