Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | SLC1A5 | Q15758 | 4/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | LAP3 | P28838 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL415523 | 0.89 | CCR6 (0.54) | CCR6PAX8IDO1SLC1A3SLC1A1 | |
| SCHEMBL417986 | 0.88 | CCR6 (0.53) | CCR6PAX8IDO1SLC1A3SLC1A1 | |
| SCHEMBL417676 | 0.83 | CCR6 (0.52) | CCR6PAX8IDO1SLC1A3SLC1A1 | |
| SCHEMBL14675316 | 0.79 | IDO1 (0.46) | IDO1SLC1A3SLC1A1ANPEPALDH1A1 | |
| SCHEMBL7667985 | 0.79 | ALDH1A1 (0.49) | IDO1SLC1A3SLC1A1ALDH1A1SLC15A1 | |
| SCHEMBL8501765 | 0.78 | CCR6 (0.45) | CCR6PAX8IDO1SLC1A3SLC1A1 | |
| SCHEMBL27515194 | 0.78 | DPP8 (0.46) | IDO1SLC1A3SLC1A1ANPEPALDH1A1 | |
| SCHEMBL7893066 | 0.77 | CCR6 (0.41) | CCR6PAX8IDO1SLC1A3SLC1A1 | |
| SCHEMBL7893100 | 0.76 | CCR6 (0.43) | CCR6PAX8IDO1SLC1A3SLC1A1 | |
| SCHEMBL759516 | 0.76 | CCR6 (0.66) | CCR6PAX8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102131814-B | (Poly) aminoalkylaminoalkylamide, alkyl-urea or alkyl-sulfonamide derivatives of epipodophyllotoxins, process for their preparation and their use in therapy as anticancer agents | PF MEDICAMENT | 2014-03-26 | — | — | CN | disclosed |