Benzamide

Benzamide

SCHEMBL27945852

NC(=O)c1ccccc1.O=C(O)c1cc[nH]n1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.55
TSHR P16473 2/20 0.55
POLB P06746 1/20 0.55
CYP3A4 P08684 1/20 0.55
PARP1 P09874 1/20 0.55
MAPT P10636 1/20 0.55
CYP2C19 P33261 1/20 0.55
RECQL P46063 1/20 0.55
BLM P54132 1/20 0.55
PMP22 Q01453 1/20 0.55
HSD17B10 Q99714 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
PARP10 Q53GL7 7/20 0.45
PARP15 Q460N3 3/20 0.41
PLA2G10 O15496 1/20 0.41
PLA2G2A P14555 1/20 0.41
MKNK1 Q9BUB5 1/20 0.39
MKNK2 Q9HBH9 1/20 0.39
NAPRT Q6XQN6 2/20 0.39
DAO P14920 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbamic Acid SCHEMBL5356506 0.85 KDM4E (0.38) L3MBTL1TSHRTDP1NAPRTDAO
SCHEMBL27609726 0.85
Benzene SCHEMBL15668588 0.85 ALOX15 (0.46) L3MBTL1TSHRPOLBMAPTHSD17B10
Hydrazine SCHEMBL20269922 0.83 KDM4E (0.39) L3MBTL1TSHRMAPTTDP1NAPRT
SCHEMBL7790 0.83
Phosphine SCHEMBL28881621 0.81 KDM4E (0.41) L3MBTL1TSHRMAPTTDP1NAPRT
SCHEMBL21837234 0.81 KDM4E (0.41) L3MBTL1TSHRMAPTTDP1NAPRT
Bromide SCHEMBL6269164 0.81
Ammonia Solution, Strong SCHEMBL20400056 0.81
Hydrochloric Acid SCHEMBL1662114 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103450154-B Substituted pyrazolecarboxylic benzamide type bisamide derivatives of one class Sulfide-containing Hindered, N-cyano group sulphur (sulfone) imine structure and its production and use NANKAI UNIVERSITY (CN) 2016-01-20 CN claimed
CN-103450154-A Double amide derivative containing sulfur ether and N-sulfur cyano (sulphone) imine structure and replacing pyrazolecarboxamide and preparing method and purpose thereof UNIV NANKAI 2013-12-18 CN claimed
CN-103450154-B Substituted pyrazolecarboxylic benzamide type bisamide derivatives of one class Sulfide-containing Hindered, N-cyano group sulphur (sulfone) imine structure and its production and use NANKAI UNIVERSITY (CN) 2016-01-20 CN disclosed
CN-103450154-B Substituted pyrazolecarboxylic benzamide type bisamide derivatives of one class Sulfide-containing Hindered, N-cyano group sulphur (sulfone) imine structure and its production and use NANKAI UNIVERSITY (CN) 2016-01-20 CN disclosed
CN-103450154-B Substituted pyrazolecarboxylic benzamide type bisamide derivatives of one class Sulfide-containing Hindered, N-cyano group sulphur (sulfone) imine structure and its production and use NANKAI UNIVERSITY (CN) 2016-01-20 CN disclosed
CN-105001085-A Method for synthesizing ethyl 4,4-difluoroacetoacetate in catalyzed mode through layered materials UNIV QUZHOU 2015-10-28 CN disclosed
CN-103450154-A Double amide derivative containing sulfur ether and N-sulfur cyano (sulphone) imine structure and replacing pyrazolecarboxamide and preparing method and purpose thereof UNIV NANKAI 2013-12-18 CN disclosed