Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.87 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.87 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.87 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.87 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | CES2 | O00748 | 1/20 | 0.61 |
| ▸ | CES1 | P23141 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.50 |
| ▸ | WNT3A | P56704 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Picolinic Acid SCHEMBL27658889 | 0.96 | LMNA (0.87) | LMNAL3MBTL1NAPRTP4HTMALDH1A1 | |
| 2-Picolinic Acid SCHEMBL5694340 | 0.96 | LMNA (0.87) | LMNAL3MBTL1NAPRTP4HTMALDH1A1 | |
| 2-Picolinic Acid SCHEMBL674837 | 0.93 | LMNA (1.00) | LMNAL3MBTL1NAPRTP4HTMALDH1A1 | |
| 2-Picolinic Acid SCHEMBL29368665 | 0.93 | — | — | |
| 2-Picolinic Acid SCHEMBL36055 | 0.93 | — | — | |
| 2-Picolinic Acid SCHEMBL7457912 | 0.93 | LMNA (1.00) | LMNAL3MBTL1NAPRTP4HTMALDH1A1 | |
| 2-Picolinic Acid SCHEMBL28737810 | 0.93 | LMNA (1.00) | LMNAL3MBTL1NAPRTP4HTMALDH1A1 | |
| 2-Picolinic Acid SCHEMBL1831091 | 0.92 | LMNA (0.80) | LMNAL3MBTL1NAPRTP4HTMALDH1A1 | |
| 2-Picolinic Acid SCHEMBL27827395 | 0.92 | LMNA (0.80) | LMNAL3MBTL1NAPRTP4HTMALDH1A1 | |
| 2-Picolinic Acid SCHEMBL27634356 | 0.92 | LMNA (0.80) | LMNAL3MBTL1NAPRTP4HTMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103442712-A | Substituted 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals | SANOFI SA | 2013-12-11 | — | — | CN | disclosed |