Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH4 | P08319 | 1/20 | 0.38 |
| ▸ | ADH7 | P40394 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 9/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CPT2 | P23786 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16526737 | 1.00 | TSHR (0.46) | TSHRFAAHTRPV1GGPS1EPHX1 | |
| SCHEMBL9520083 | 1.00 | TSHR (0.46) | TSHRFAAHTRPV1GGPS1EPHX1 | |
| SCHEMBL1783923 | 1.00 | TSHR (0.46) | TSHRFAAHTRPV1GGPS1EPHX1 | |
| SCHEMBL1410637 | 0.98 | TSHR (0.42) | TSHRFAAHTRPV1GGPS1EPHX1 | |
| SCHEMBL1410490 | 0.91 | TSHR (0.42) | TSHRFAAHTRPV1EPHX1ADH1B | |
| SCHEMBL3372731 | 0.83 | TDP1 (0.33) | FFAR1CPT2TDP1 | |
| SCHEMBL27355281 | 0.82 | TSHR (0.46) | TSHRFAAHTRPV1FFAR1CPT2 | |
| SCHEMBL1410793 | 0.80 | — | — | |
| SCHEMBL1782782 | 0.80 | FDPS (0.45) | TSHRFAAHTRPV1GGPS1FDPS | |
| SCHEMBL16940325 | 0.80 | TSHR (0.70) | TSHRFAAHTRPV1GGPS1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103393691-A | Anti-inflammatory agents | UNIV CAMBRIDGE TECH | 2013-11-20 | — | — | CN | disclosed |