Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.88 |
| ▸ | LMNA | P02545 | 5/20 | 0.88 |
| ▸ | HPGD | P15428 | 3/20 | 0.88 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.88 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.88 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.88 |
| ▸ | RECQL | P46063 | 1/20 | 0.88 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 5/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | PGR | P06401 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | PDE4A | P27815 | 1/20 | 0.62 |
| ▸ | HRH1 | P35367 | 1/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cearoin SCHEMBL4928735 | 0.93 | MAPT (1.00) | MAPTLMNAHPGDKDM4EHSD17B10 | |
| Cearoin SCHEMBL29874650 | 0.93 | MAPT (1.00) | MAPTLMNAHPGDKDM4EHSD17B10 | |
| SCHEMBL9339940 | 0.92 | MAPT (0.84) | MAPTLMNAHPGDKDM4EHSD17B10 | |
| SCHEMBL12082118 | 0.87 | MAPT (0.77) | MAPTLMNAHPGDKDM4EHSD17B10 | |
| Methane SCHEMBL28771418 | 0.86 | LMNA (0.70) | MAPTLMNAHPGDKDM4EHSD17B10 | |
| SCHEMBL29229967 | 0.86 | MAPT (0.70) | MAPTLMNAHPGDKDM4EHSD17B10 | |
| SCHEMBL2586221 | 0.86 | LMNA (0.70) | MAPTLMNAHPGDKDM4EHSD17B10 | |
| SCHEMBL12082139 | 0.84 | MAPT (0.73) | MAPTLMNAHPGDKDM4EHSD17B10 | |
| SCHEMBL812177 | 0.84 | MAPT (0.73) | MAPTLMNAHPGDKDM4EHSD17B10 | |
| SCHEMBL28771416 | 0.84 | MAPT (0.68) | MAPTLMNAHPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103396299-B | Novel flavonoid compounds and application thereof in preparation of drug for resisting ischemic heart disease | UNIV JIANGXI TRAD CHINESE MED | 2015-06-24 | — | — | CN | disclosed |
| CN-103396299-A | Novel flavonoid compounds and application thereof in preparation of drug for resisting ischemic heart disease | UNIV JIANGXI TRAD CHINESE MED | 2013-11-20 | — | — | CN | disclosed |